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Single-Cell Genomics and Epigenomics: Technologies and Applications in Plants

信息来源:     发布时间:2020-06-16

Author links open overlay panelChengLuo,   Alisdair R.Fernie,   JianbingYan

Trends in Plant Science

Available online 9 June 2020



Highlights


  • The rapidly developing fields of single-cell genomics and epigenomics provide powerful approaches to dissect cell heterogeneity in plants.

  • The sensitivity and specificity of detecting single-nucleotide variations and copy-number variations via single-cell whole-genome amplification technologies have been continuously improving over the past decades. Recent applications highlight their feasibility and utility in plant single-cell genomics.

  • Recent technical advances in single-cell epigenomics have enabled comprehensive and accurate profiling of diverse epigenomic features. The cell-specific epigenome facilitates the dissection of molecular mechanisms underlying biological processes in plants.

  • Overcoming current technical issues and integrating multiomic single-cell sequencing data in plants will provide far greater understanding of plant functional genomics.

全文链接: https://www.sciencedirect.com/science/article/pii/S1360138520301497


 


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